学术论文： |
发表文章（近三年，10篇以内） 1．Hua Guo,Yang Li,Junlian Gu,Yue Wang,Lianqin Liu,Ping zhang ,Yanan Liu*. Effect of VEGF siRNA and wide-type p53 co-expressing plasmid in MDA-MB-231 cells. Molecular medicine reports 2016 Jan;13(1):461-8. 2．Guo Hua, Liu Yanan, Gu Julian, Wang Yue, Liu Lianqin, Zhang Ping, Li Yang. Endostatin inhibits the growth and migration of 4T1 mouse breast cancer cells by skewing macrophage polarity toward the M1 phenotype. Cancer Immunol Immunother. 2016 Jun;65(6):677-88. 3．Ma L, Xu Y, Su J, Yu H, Kang J, Li H, Li X, Xie Q, Yu C, Sun L, Li Y. Autophagic flux promotes cisplatin resistance in human ovarian carcinoma cells through ATP-mediated lysosomal function. Int J Oncol. 2015 Nov;47(5):1890-900. 4. Ya-Nan Liu , Jun-Lian Gu , Meng-Shi Ma , Hua Guo , Long Liu , Li-Rong Guo,Yue Wang,Yang Li.Diterpenoid B derived from plectranthus excisus block melanoma cell cycle in B16 melanoma cell line.Molecular medicine reports 2015,12（3）:4578-83 5．Gu J, Wang B, Liu Y, Zhong L, Tang Y, Guo H, Jiang T, Wang L, Li Y*, Cai L*.Murine Double Minute 2 siRNA and wild-type p53 gene therapy interact positivelywith zinc on prostate tumours in vitro and in vivo. Eur J Cancer. ,2014. pii: S0959-8049(14)00009-4 6．Junlian Gu , Yufeng Tang , Yanan Liu , Hua Guo , Yue Wang, Lu Cai , Yang Li* ,Bo Wang*. Murine double minute 2 siRNA and wild-type p53 gene therapy enhances sensitivity of the SKOV3/DDP ovarian cancer cell line to cisplatin chemotherapy in vitro and in vivo. Cancer Letters. 2013. S0304-3835(13)00740-4, 7. Zhang, Shuang，Liu, Xianhong，Zhang, Yong，Cheng, Ying(*)，Li, Yang*，RNAi screening identifies KAT8 as a key molecule important for cancer cell survival，INTERNATIONAL JOURNAL OF CLINICAL AND EXPERIMENTAL PATHOLOGY,2013,6（5）：870-877. 8. Li, Xin，Li, Yang，Wang, Bo，Ji, Kun，Liang, Zuowen，Guo, Baofeng，Hu, Jiadi，Yin, Di，Du,Yanwei，Kopecko, Dennis J.，Kalvakolanu, Dhananjaya V.，Zhao, Xuejian，Xu, Deqi，Zhang, Ling，Delivery of the co-expression plasmid pEndo-Si-Stat3 by attenuated Salmonella serovar typhimurium forprostate cancer treatment，Journal of Cancer Research and Clinical Oncology，2013，139（6）：971-980. 9．Li, Xin，Li, Yang，Hu, Jiadi，Wang, Bo，Zhao, Lijing，Ji, Kun，Guo, Baofeng，Yin, Di，Du,Yanwei，Kopecko, Dennis J.，Kalvakolanu, Dhananjaya V.，Zhao, Xuejian，Xu, Deqi(*)，Zhang, Ling(*)，Plasmid-based E6-specific siRNA and co-expression of wild-type p53 suppresses the growth of cervical cancer in vitro and in vivo，Cancer Letters，2013，335（1）：242-250。 10. Yin, Di，Li, Yang，Lin, Hang，Guo, Baofeng，Du, Yanwei，Li, Xin，Jia, Huijie，Zhao,Xuejian，Tang, Jun，Zhang, Ling，Functional graphene oxide as a plasmid-based Stat3 siRNA carrier inhibits mouse malignant melanoma growth in vivo，Nanotechnology，2013，24（10）。 |
获奖情况： |
1）癌基因-特异siRNA联合抑癌基因共表达质粒综合靶向治疗实体肿瘤机制研究,吉林省自然科学学术成果一等奖, 20151012, 2015.10，第二名 2）李扬，顾俊莲，汲坤，江涛，王波，刘亚男《减毒沙门氏菌携带共表达siRNA-mdm2与p53质粒抗前列腺癌的实验研究》吉林省自然科学学术成果奖二等奖 2014年 3）王波，邵晨，罗琪，顾俊莲，李馨，蔡露，谭毅，李扬（指导教师）《低剂量镉对机体影响研究》吉林省自然科学学术成果奖一等奖2012年 2）李晓萌、李江、孙自捷、汪小莞、辻一郎、王伟华、李扬、潘莹，hZimp10在前列腺癌相关信号通路中的作用机制研究，吉林省科技进步二等奖, 2012 3)赵雪俭、张灵、高洪文、高丽芳、计国义、赵丽娟、王伟华、李晓萌、李扬、赵丹、孔祥波、刘艳波、潘玉琢、孟艳、梁作文.前列腺癌早期诊断与诊治基础研究, 中华医学科技二等奖, 2009 4)赵雪俭、张灵、高丽芳、赵丹、李扬、赵丽娟、郭宝锋、汲坤、刘艳波. Stat3-SiRNA及其共表达质粒的抗前列腺癌作用与机制,吉林省科技进步二等奖, 2009 5)李晓萌、李扬、李江、张灵、张海峰、王洪亮、王伟华、高洪文.恢复前列腺癌TGFβ-Smad信号通路的新型分子靶向研究,吉林省科技进步三等奖, 2009 6)赵雪俭、王伟华、李扬、赵丹、高洪文、计国义、王金国、高丽芳、赵丽娟、张灵、刘春喜、潘玉琢.前列腺癌早期发现，早期诊治与基础研究一体化平台的建立与应用,教育部科技进步二等奖, 2004 |
