所在学科专业：

免疫学

研究方向：

1. 固有免疫应答

2. 细胞因子

3. 黏膜免疫

讲授课程：

本科生：医学免疫学

研究生：高级免疫学理论与技术

教育经历：

2003.9-2008.7必赢网址bwi437，预防医学系，本科/医学学士

2009.3-2014.12英国格拉斯哥大学(University of Glasgow)，感染、免疫和炎症研究所，研究生/博士

工作经历：

2014.12-2016.09 437ccm必赢国际 讲师

2016.09-至今    必赢网址bwi437 437ccm必赢国际 副教授

科研项目：

1.国家自然科学基金青年项目，II型固有淋巴细胞通过T细胞非依赖途径在特发性肺纤维化中的作用及细胞和分子机制研究、2016/01-2018/12

2.白介素因子-33及其抗体的临床应用的可行性及安全性评价，2015/05-2019/04

学术论文：

发表文章（近三年，10篇以内）

1. Song Y, Liu Y, Pan Y, Yuan X, Chang P, Tian Y, Cui W, Li D*. The effect of long chain polyunsaturated fatty acid supplementation on intelligence in low birth weight infant during lactation: A meta-analysis. PLoS One. 2018;13(4):e0195662. doi: 10.1371/journal.pone.0195662. PubMed PMID: 29634752. (IF: 2.80)

2. Li D*, Gao X, Gu J, Tian Y, Liu Y, Jin Z, Yan D, Chen YG*, Zhu X*. A Novel Application of Ti-Substituted Polyoxometalates: Anti-Inflammatory Activity in OVA-Induced Asthma Murine Model. Bioinorg Chem Appl. 2016;2016:3239494. doi: 10.1155/2016/3239494. PubMed PMID: 27436993. (IF: 1.49)

3. Cui W ^#, Zhang P ^#, Gu J, Tian Y, Gao X, Liu Y, Jin Z, Yan D, Zhu X*, Li D*. Vitamin A Deficiency Promotes Inflammation by Induction of Type 2 Cytokines in Experimental Ovalbumin-Induced Asthma Murine Model. Inflammation. 2016. doi: 10.1007/s10753-016-0415-2. PubMed PMID: 27525423. (IF: 2.62)

4. Zhang L ^（#）, Li D ^（#）, Li X, Hu L, Cheng M, Xia F, Gong P, Wang B, Ge J, Zhang H, Cai R, Wang Y, Sun C, Feng X, Lei L, Han W*, Gu J*. LysGH15 kills Staphylococcus aureus without being affected by the humoral immune response or inducing inflammation. Sci Rep. 2016;6:29344. doi: 10.1038/srep29344. PubMed PMID: 27385518. (IF: 5.23)

5. Li D ^（#）, Guabiraba R ^（#）, Besnard AG, Komai-Koma M, Jabir MS, Zhang L, Graham GJ, Kurowska-Stolarska M, Liew FY, McSharry C*, Xu D*. IL-33 promotes ST2-dependent lung fibrosis by the induction of alternatively activated macrophages and innate lymphoid cells in mice. J Allergy Clin Immunol. 2014;134(6):1422-32 e11. doi: 10.1016/j.jaci.2014.05.011. PubMed PMID: 24985397. (IF: 12.49)

6. Jabir MS, Ritchie ND, Li D, Bayes HK, Tourlomousis P, Puleston D, Lupton A, Hopkins L, Simon AK, Bryant C, Evans TJ*. Caspase-1 cleavage of the TLR adaptor TRIF inhibits autophagy and beta-interferon production during Pseudomonas aeruginosa infection. Cell Host Microbe. 2014;15(2):214-27. doi: 10.1016/j.chom.2014.01.010. PubMed PMID: 24528867. (IF: 12.55)

7. Komai-Koma M, Li D, Wang E, Vaughan D, Xu D*. Anti-Toll-like receptor 2 and 4 antibodies suppress inflammatory response in mice. Immunology. 2014;143(3):354-62. doi: 10.1111/imm.12312. PubMed PMID: 24801735; PubMed Central PMCID: 24801735. (IF: 4.08)

8. Jabir MS, Hopkins L, Ritchie ND, Ullah I, Bayes HK, Li D, Tourlomousis P, Lupton A, Puleston D, Simon AK, Bryant C, Evans TJ*. Mitochondrial damage contributes to Pseudomonas aeruginosa activation of the inflammasome and is downregulated by autophagy. Autophagy. 2015;11(1):166-82. doi: 10.4161/15548627.2014.981915. PubMed PMID: 25700738; PubMed Central PMCID: 24528867. (IF: 11.75)

9. Chang P, Zhang B, Shao L, Song W, Shi W, Wang L, Xu T, Li D, Gao X, Qu Y, Dong L*, Wang J*. Mesenchymal stem cells over-expressing cxcl12 enhance the radioresistance of the small intestine. Cell Death Dis. 2018;9(2):154. doi: 10.1038/s41419-017-0222-1. PubMed PMID: 29402989. (IF: 5.96)

Komai-Koma M ^(#), Wang E ^(#), Kurowska-Stolarska M, Li D, McSharry C, Xu D*. Interleukin-33 promoting Th1 lymphocyte differentiation dependents on IL-12. Immunobiology. 2016;221(3):412-7. doi: 10.1016/j.imbio.2015.11.013. PubMed PMID: 26688508. (IF: 2.78)

著作教材：

1.

2.

获奖情况：

xxxxx、xxxxxx、xxxxxx、

社会兼职：